Periodontal Diseases

According to prevalence data at least 37% of the adult population suffer from moderate levels of chronic periodontitis (with 4-6mm pocketing), while 8% of the population suffer from severe periodontitis (with pocketing exceeding 6mm).

Similar to teeth, inflammation may also occur at dental implant sites. The different stages of inflammatory disease are then called peri-implant mucositis and peri-implantitis depending on the involvement of alveolar bone, peri-implantitis being the more severe stage of the disease.

The treatment strategy for periodontal disease remains the same whether a tooth or implant is affected.

The periodontal biofilm comprising various gram-positive and gram-negative bacteria plays a primary role in the initiation and progression of these diseases. Studies investigating the microbiologic profiles across these indications have indicated that peri-implantitis represents a heterogeneous and more complex infection with predominantly non-culturable gram-negative species compared with periodontitis.

Disease progression may also be influenced by systemic conditions like diabetes mellitus, obesity and history of smoking in chronic periodontitis. Systematic studies have shown that in smokers and diabetic patients with chronic periodontitis, adjunctive use of local antimicrobials improved efficacy of non-surgical treatment in periodontal therapy in reducing pocket depth and improving clinical attachment level (CAL) at sites presenting PD ≥5 mm before treatment.

The ultimate goal of periodontal therapy is to eliminate supra-gingival and sub-gingival plaque (bacterial infection) and arrest the progression of periodontal disease. Mechanical root debridement is the cornerstone of periodontal therapy as it aims at removal of sub-gingival biofilm and calculus, which together with the patient’s oral hygiene practices will prevent bacterial re-colonization and formation of supra-gingival biofilms. Debridement is carried out with curettes and scalers and staged in different sessions. This conventional non-surgical treatment in periodontal therapy has proven to be the gold standard treatment in chronic periodontitis.

Treatment outcomes depend on the ability of the dentist and/or dental hygienist to effectively remove all sub-gingival biofilm and calculus. This is a complicated procedure often compromised by pain, tough calculus and access.

Perisolv facilitates for the dentist/hygienist in removing the biofilm/calculus as it dissolve the necrotic tissue and softens the calculus while leaving healthy tissues intact.


PeriSolv is a new cleaning gel used in addition to mechanical debridement.

Elimination of the biofilm is key for the treatment success of periodontitis, peri-implant muscositis and peri-implantitis.